Anika Singh Lemar Confronts Connecticut’s Housing Crisis

Anika Singh Lemar Confronts Connecticut’s Housing Crisis

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Clinical Professor of Law Anika Singh Lemar talks about the struggle to build more affordable housing in Connecticut and the three clinics she leads at the Law School that work on housing issues. She also discusses her ideas about making it easier to build housing.

https://law.yale.edu/yls-today/news/podcast-anika-singh-lemar-confronts-connecticuts-housing-crisis

YJBM Science News 31: Clues to Cancer Care

YJBM Science News 31: Clues to Cancer Care

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This week’s episode of the YJBM Science News podcast is all about papers that identify or help narrow down potential new targets and tools for cancer therapeutics. From protein modifications to autoantibodies to epigenetic markers and more, join co-hosts Majo and Roxanna as they break down recent Yale-affiliated biological and biomedical research.

Papers featured in this episode:
“Turnover atlas of proteome and phosphoproteome across mouse tissues and brain regions” – https://doi.org/10.1016/j.cell.2025.02.021
https://medicine.yale.edu/news-article/protein-turnover-mapping-may-offer-clues-for-alzheimers-cancer-treatment/
“A lupus-derived autoantibody that binds to intracellular RNA activates cGAS-mediated tumor immunity and can deliver RNA into cells” – https://doi.org/10.1126/scisignal.adk3320
https://medicine.yale.edu/news-article/lupus-related-antibody-shows-promise-in-enhancing-cancer-treatment-efficacy/
“BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filaments” – https://doi.org/10.1038/s41586-025-08749-x
https://news.yale.edu/2025/03/26/how-inherited-cancer-risks-can-be-used-effective-personalized-therapy
“An in vivo screen identifies NAT10 as a master regulator of brain metastasis” – https://doi.org/10.1126/sciadv.ads6021
https://medicine.yale.edu/news-article/a-genetic-screen-identifies-a-new-master-regulator-of-brain-metastasis/

Read more about YJBM at:
https://medicine.yale.edu/yjbm/

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The Immunology of Long COVID: An Interview with Dr. Lindsay McAlpine and Dr. Keyla Sá

The Immunology of Long COVID: An Interview with Dr. Lindsay McAlpine and Dr. Keyla Sá

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Why do some individuals continue to experience debilitating neurologic symptoms long after their initial COVID-19 infections? How might our own immune systems be the culprit? In this episode of the YJBM podcast, we learn more about the post-acute infection syndrome known as “long COVID” and the challenges associated with trying to understand its underlying mechanisms. Join co-hosts Shivani and Roxanna as they interview Dr. Lindsay McAlpine and Dr. Keyla Sá, researchers at the Yale University School of Medicine, about their work investigating the pathophysiology of long COVID-associated neurologic symptoms.

Papers/preprints mentioned in this interview:
“Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19” – https://doi.org/10.1212/NXI.0000000000200244
“A causal link between autoantibodies and neurological symptoms in long COVID” – https://doi.org/10.1101/2024.06.18.24309100

Keep up with Dr. McAlpine’s work:
https://medicine.yale.edu/lab/mcalpine/
https://medicine.yale.edu/neurology/research/covid-mind-study/
https://x.com/mcalpinelabyale
https://bsky.app/profile/drlynseymcalpine.bsky.social

Keep up with Dr. Sá’s work:
https://medicine.yale.edu/lab/iwasaki/
https://x.com/keylas3
https://x.com/VirusesImmunity
https://bsky.app/profile/virusesimmunity.bsky.social

Read more about YJBM at:
https://medicine.yale.edu/yjbm/

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From Learning to Leading | Laura Sievert Hesseltine | Continual Forward Progress

From Learning to Leading | Laura Sievert Hesseltine | Continual Forward Progress

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Laura Sievert Hesseltine is the Executive Director of Arts Quincy, the oldest arts council in the U.S., where she champions community engagement and cultural transformation. With a background in corporate marketing and a passion for creativity, Laura shares her journey from leading large-scale retail marketing campaigns to revitalizing the arts sector in rural Illinois. She discusses the power of the arts in shaping communities, the importance of making culture accessible to all, and how she applies business principles to nonprofit leadership. Laura also reflects on connected leadership, continuous learning, and how small, intentional steps can drive meaningful change.

YJBM Science News 30: Reproductive Health and Immunology

YJBM Science News 30: Reproductive Health and Immunology

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In this week’s installment of YJBM Science News, Majo and Roxanna discuss recent Yale-affiliated research about contraceptives, fertility, and immunology! Can our genetic variants help us predict which birth control method would be the most effective? What can the gut microbiome tell us about the immune systems of multiple sclerosis patients before and after undergoing immunotherapy treatment? Join us as we explore not only the answers to these questions, but also as we learn more about the trials and tribulations of data generation!

Papers featured in this episode:

“Pharmacogenomics of the Etonogestrel Contraceptive Implant: A Genome-Wide Association Study of Steady-State Etonogestrel Concentrations” – https://doi.org/10.1097/og9.0000000000000066
https://medicine.yale.edu/news-article/analyzing-genetics-may-lead-to-better-contraceptive-experiences-for-women/

“Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13” – https://doi.org/10.1073/pnas.2425952122
https://news.yale.edu/2025/03/03/scientists-discover-how-naturally-occurring-mechanism-hampers-fertility

“A single-cell atlas of circulating immune cells over the first 2 months of age in extremely premature infants” – https://doi.org/10.1126/scitranslmed.adr0942
https://medicine.yale.edu/news-article/new-insights-into-preterm-infant-immunity-could-inform-care/

“Alterations in Gut Microbiome-Host Relationships After Immune Perturbation in Patients With Multiple Sclerosis” – https://doi.org/10.1212/NXI.0000000000200355
https://medicine.yale.edu/news-article/gut-microbiome-changes-linked-to-multiple-sclerosis-ms-new-study-finds/

Read more about YJBM at:
https://medicine.yale.edu/yjbm/

Follow us on instagram!
https://www.instagram.com/theyjbm/

A Tale of Two Viruses: Interview with Sasha Tabachnikova

A Tale of Two Viruses: Interview with Sasha Tabachnikova

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What do COVID and mono have in common? How can infectious diseases impact our health for life? How does a dancer end up doing basic science research? Join our hosts Isha Yardi and Elaine Yang in conversation with Sasha Tabachnikova about her work as a PhD student in the Iwasaki Lab. Today, she is our guide through the evolving landscape of research on post-acute infection syndromes.

Learn about YJBM here: https://medicine.yale.edu/yjbm/

Viruses and Autoimmunity issue: https://medicine.yale.edu/news-article/yjbms-december-2024-issue-focuses-on-viruses-and-autoimmunity/

Our Instagram: https://www.instagram.com/theyjbm/

Improving obstetric anesthesia through teaming

Improving obstetric anesthesia through teaming

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In this episode, we explore the concept of a highly functional team, its characteristics, and the importance of fostering interdisciplinary teamwork among healthcare professionals such as anesthesiologists, obstetricians, nurses, and others. Dr. Girnius emphasizes that such collaboration enhances communication and efficiency and improves patient outcomes. Additionally, we discuss the process of identifying and implementing what needs to change while addressing the challenges associated with introducing change within our healthcare system.

Improving Obstetric Anesthesia Care Through Teaming and Improvement Science
https://pubmed.ncbi.nlm.nih.gov/39325012/

Preoperative Multidisciplinary Team Huddle Improves Communication and Safety for Unscheduled Cesarean Deliveries: A System Redesign Using Improvement Science
https://pubmed.ncbi.nlm.nih.gov/39269911/

Leading the Way | Jigar Shah | Driving Clean Energy Innovation Through Finance and Leadership

Leading the Way | Jigar Shah | Driving Clean Energy Innovation Through Finance and Leadership

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Jigar Shah, a trailblazer in clean energy finance, shares his insights on scaling sustainable technology and aligning capital with long-term impact. Drawing from his experience as the founder of SunEdison and leader of the U.S. Department of Energy’s Loan Programs Office, Jigar discusses the challenges of commercializing clean energy solutions and the role of strategic leadership in accelerating the transition. He emphasizes the importance of financial innovation, building high-performing teams, and navigating industry shifts to drive lasting change. This episode offers valuable lessons on financing the clean energy future and leading with purpose.

Leading the Way | Jens Molbak | Harnessing Tri-Sector Innovation for Greater Impact

Leading the Way | Jens Molbak | Harnessing Tri-Sector Innovation for Greater Impact

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Jens Molbak, founder of Coinstar, WinWin, and NewImpact, shares his vision for leveraging tri-sector innovation aligning resources from businesses, nonprofits, and government to create systemic change. He discusses how his experience building Coinstar shaped his understanding of scalable impact and how NewImpact is pioneering a data-driven approach to solve complex societal challenges. Jens highlights the importance of collaboration across sectors, identifying underutilized assets, and shifting mindsets to unlock greater efficiency and innovation. This episode offers valuable insights on designing solutions that maximize shared value and create lasting social and economic benefits.