Category: Yale Anesthesiology

This collection features interviews with anesthesiologists and other experts in which we discuss topics ranging from basic anesthesia to subspecialty-related topics.

Electronic Maternal Alerting System

Electronic Maternal Alerting System

In this episode, Dr. Thomas Klumpner, whose research interests involve using technology to detect childbirth complications before they become life-threatening, discusses with us his research titled: Use of a Novel Electronic Maternal Surveillance System and the Maternal Early Warning Criteria to Detect Severe Postpartum Hemorrhage

Use of a Novel Electronic Maternal Surveillance System and the Maternal Early Warning Criteria to Detect Severe Postpartum Hemorrhage https://pubmed.ncbi.nlm.nih.gov/32022745/

Singh et al., A validation study of the CEMACH recommended modified early obstetric warning system (MEOWS) https://pubmed.ncbi.nlm.nih.gov/22066604/

Klumpner, T, stal. User Perceptions of an Electronic Maternal Alerting System. A A Pract. 2020;14(11):e01308 – https://pubmed.ncbi.nlm.nih.gov/32935951/

Use of a novel electronic maternal surveillance system to generate automated alerts on the labor and delivery unit https://pubmed.ncbi.nlm.nih.gov/29945569/

Consensus Guidelines: Postdural Puncture Headache

Consensus Guidelines: Postdural Puncture Headache

In this episode, Dr. Vishal Uppal, whose primary research interests are improving the safety and efficacy of regional anesthesia techniques in high-risk patient populations, discussed his article Consensus Practice Guidelines on Postdural Puncture Headache From a Multisociety, International Working Group: A Summary Report.

Consensus guidelines
https://pubmed.ncbi.nlm.nih.gov/37581893/
Atypical headache following dural puncture in obstetric
https://pubmed.ncbi.nlm.nih.gov/24934311/
A prospective controlled study of continuous spinal analgesia versus repeat epidural analgesia after accidental dural puncture in labour
https://pubmed.ncbi.nlm.nih.gov/22153280/
One patch or more? Defining success in treatment of post-dural puncture headache
https://pubmed.ncbi.nlm.nih.gov/28089183/
Sphenopalatine ganglion block for postdural puncture headache
https://pubmed.ncbi.nlm.nih.gov/19413836/
Major Neurologic Complications Associated With Postdural Puncture Headache in Obstetrics: A Retrospective Cohort Study
https://pubmed.ncbi.nlm.nih.gov/31335402/
The volume of blood for epidural blood patch in obstetrics: a randomized, blinded clinical trial
https://pubmed.ncbi.nlm.nih.gov/21596867/

Trauma Informed Care

Trauma Informed Care

In this episode, Dr. Tracey Vogel, an obstetric anesthesiologist who is very well-versed in a topic we should all know about, discusses trauma-informed care. What is trauma-informed care, and how can we become a trauma-informed care unit? These and many more questions are addressed during this Podcast. “A service that is not trauma-informed is trauma denied.”

Trauma-Informed Care on Labor and Delivery
https://pubmed.ncbi.nlm.nih.gov/34776109/
Antepartum and intrapartum risk factors and the impact of PTSD on mother and child
https://pubmed.ncbi.nlm.nih.gov/33456935/
Nocebo-induced hyperalgesia during local anesthetic injection
https://pubmed.ncbi.nlm.nih.gov/20042440/
The relationship between women’s intention to request labor epidural analgesia, actually delivering with labor epidural analgesia, and Postpartum depression at six weeks
https://pubmed.ncbi.nlm.nih.gov/28930940/
Impact of patient choice
https://pubmed.ncbi.nlm.nih.gov/30867278/
Patient choice compared to no choice (“Deception study”)
https://pubmed.ncbi.nlm.nih.gov/28486595/
Trauma-Informed Care During Pregnancy and Birth
Pain during cesarean delivery: A patient-related prospective observational study assessing the incidence and risk factors for intraoperative pain and intravenous medication administration
https://pubmed.ncbi.nlm.nih.gov/37865217/

Maternal – Fetal Interventions

Maternal – Fetal Interventions

In this episode, Dr. Mark Rollins and Dr. Chatterjee, two leading experts in anesthesia for maternal-fetal intervention, share their knowledge with us. Specifically, we discussed fetal benefits and preoperative, intraoperative, and postoperative management for this delicate procedure in which two patients are undergoing surgical intervention under our care. Should we provide analgesia directly or indirectly to the fetus? How can we achieve the tenet goal of excellent uterine relaxation without compromising placental perfusion? Is the use of Sugammadex warranted for midgestation fetal interventions? These and much more were discussed during this Podcast.

Anesthesia for Maternal-Fetal Interventions: A Consensus Statement
https://pubmed.ncbi.nlm.nih.gov/33048913/

Survey of Fetal Therapy Centers in the North American Fetal Therapy Network.

https://pubmed.ncbi.nlm.nih.gov/33827094/

Sugammadex Administration in Pregnant Women and Women of Reproductive Potential: A Narrative Review

https://pubmed.ncbi.nlm.nih.gov/31283616/

Society for Obstetric Anesthesia and Perinatology
Statement on Sugammadex during pregnancy and lactation
https://www.soap.org/assets/docs/SOAP_Statement_Sugammadex_During_Pregnancy_Lactation_APPROVED.pdf

Sugammadex Use for Reversal in Nonobstetric
Surgery During Pregnancy: A Reexamination of the
Evidence

https://pubmed.ncbi.nlm.nih.gov/37205805/

A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele (MOMs trial)

https://pubmed.ncbi.nlm.nih.gov/21306277/

The Dural Puncture Epidural

The Dural Puncture Epidural

In this episode, Dr. B Amnon Berger shared the results of his study – Epidural catheter replacement rates with dural puncture epidural labor analgesia compared with epidural analgesia without dural puncture: a retrospective cohort study. Besides, we discussed the benefits of a dural puncture epidural technique and how it differs from the combined spinal-epidural technique.

Dr. Ammon study

https://pubmed.ncbi.nlm.nih.gov/36030558/

Importance of a working labor epidural

https://pubmed.ncbi.nlm.nih.gov/34106837/

CSE first described

https://pubmed.ncbi.nlm.nih.gov/7468971/

CSE/DPE techniques review
https://pubmed.ncbi.nlm.nih.gov/10594432/

Epidural vs CSE

https://pubmed.ncbi.nlm.nih.gov/9392696/

https://pubmed.ncbi.nlm.nih.gov/15321183/

https://pubmed.ncbi.nlm.nih.gov/15477051/

Epidural vs. DPE

https://pubmed.ncbi.nlm.nih.gov/28622178/

https://pubmed.ncbi.nlm.nih.gov/28067707/

https://pubmed.ncbi.nlm.nih.gov/35157756/

https://pubmed.ncbi.nlm.nih.gov/37526934/

DPE + CEI vs PIEB

https://pubmed.ncbi.nlm.nih.gov/32282386/

Pain management for Pregnant people with opioid use disorder

Pain management for Pregnant people with opioid use disorder

In this episode, Dr. Grace Lim, Associate professor and the Chief of the Obstetric Anesthesia division at the University of Pittsburgh, whose research is aimed at eliminating pain and suffering in special populations, optimizing perioperative medication use, and personalizing patient care, discussed with us two of her articles related to pain management of patients with and without opioid use disorder. Unfortunately, there is a big gap in knowledge and consensus when caring for patients with a history of opioid use disorder. In this episode, we discussed some of them.

References
CDC – About Opioid Use During Pregnancy
https://www.cdc.gov/pregnancy/opioids/basics.html
Associations between postpartum pain type, pain intensity and opioid use in patients with and without opioid use disorder: a cross-sectional study
https://pubmed.ncbi.nlm.nih.gov/36371258/

A Systematic Scoping Review of Peridelivery Pain Management for Pregnant People With Opioid Use Disorder: From the Society for Obstetric Anesthesia and Perinatology and Society for Maternal-Fetal Medicine
https://pubmed.ncbi.nlm.nih.gov/36135926/

Labor Pain, Analgesia, and Postpartum Depression:
Are We Asking the Right Questions?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080613/

Other resources related to OUD
Buprenorphine versus Methadone for Opioid Use Disorder in Pregnancy
https://pubmed.ncbi.nlm.nih.gov/36449419/
Post-cesarean delivery pain. Management of the
opioid-dependent patient before, during and after
cesarean delivery
https://pubmed.ncbi.nlm.nih.gov/36449419/

Maternal Mental Health

Maternal Mental Health

In this episode, Dr. Katrina Furey, a board-certified adult psychiatrist who offers psychotherapy, medication management, and expert consultation for women with depression, anxiety, premenstrual dysphoric disorder (PMDD), perinatal mood and anxiety disorders (including OCD), birth trauma, and menopausal mood and anxiety disorders. Besides, she is part of Access Mental Health for Moms CT. This consultation service offers real-time psychiatric consultation to medical providers when patients present with mental health and substance use concerns.

Here are the links to the studies mentioned during our Podcast:
Access Mental Health for Moms CT
https://www.accessmhct.com
Newspaper link
https://www.cnn.com/2023/08/10/health/suicide-deaths-record-high-2022/index.html
The Collision of Mental Health, Substance Use Disorder, and Suicide
https://pubmed.ncbi.nlm.nih.gov/33957654/
Associations between postpartum pain type, pain intensity, and opioid use in patients with and without opioid use disorder: a cross-sectional study
https://www.bjanaesthesia.org/article/S0007-0912(22)00570-0/fulltext
Analyze Scripts Podcast
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Frequency and Risk Factors for Difficult intubation in Women Undergoing General Anesthesia for Cesarean Delivery

Frequency and Risk Factors for Difficult intubation in Women Undergoing General Anesthesia for Cesarean Delivery

In this episode, Dr. Sharon Reale shares with us the results of her study titled Frequency and Risk Factors for Difficult Intubation in Women Undergoing General Anesthesia for Cesarean Delivery: A Multicenter Retrospective Cohort Analysis. As Dr. Reale pointed out during this Podcast, most of the available literature regarding the obstetric airway comes from data outside of the United States. Dr. Reale’s study strength resides in the use of a centralized extensive database, the Multicenter Perioperative Outcomes Group (MPOG).

Here are the links to the studies mentioned during our Podcast:
Frequency and Risk Factors for Difficult Intubation in Women Undergoing General Anesthesia for Cesarean Delivery: A Multicenter Retrospective Cohort Analysis- https://pubmed.ncbi.nlm.nih.gov/35188971/
Serious Complications Related to Obstetric Anesthesia-
https://pubmed.ncbi.nlm.nih.gov/24845921/
Airway changes during labor and delivery – https://pubmed.ncbi.nlm.nih.gov/18292672/
Failed intubation in obstetrics: a self-fulfilling prophecy? –https://pubmed.ncbi.nlm.nih.gov/17126002/
Anesthesia-related maternal mortality in the United States: 1979-2002. – https://pubmed.ncbi.nlm.nih.gov/21173646/
Pregnancy-Related Mortality in the United States, 2011–2013- https://pubmed.ncbi.nlm.nih.gov/28697109/

Obstructive Sleep Apnea in Pregnancy

Obstructive Sleep Apnea in Pregnancy

In this episode, Dr. Jennifer Dominguez, a leading expert in topics related to morbid obesity, particularly Obstructive Sleep Apnea (OSA), talks with us regarding the importance of early recognition and management of OSA during Pregnancy. To guide our discussion, we conversed regarding the recently published consensus statement titled- The Society of Anesthesia and Sleep Medicine and the Society for Obstetric Anesthesia and Perinatology Consensus Guideline on the Screening, Diagnosis, and Treatment of Obstructive Sleep Apnea in Pregnancy publication is an excellent reference for all those caring for patients with a known or suspected diagnosis of OSA. In this episode, we emphasized the intra (e.g., intrathecal morphine) and postoperative care (e.g., monitoring) of the parturient with a known or suspected OSA.

Here are the links to the study discussed during our Podcast:
Society of Anesthesia and Sleep Medicine and the Society for Obstetric Anesthesia and Perinatology Consensus Guideline on the Screening, Diagnosis, and Treatment of Obstructive Sleep Apnea in Pregnancy
https://pubmed.ncbi.nlm.nih.gov/37411038/
Obesity in Pregnancy – https://pubmed.ncbi.nlm.nih.gov/35857661/
Monitoring
Quantifying the incidence of clinically significant respiratory depression in women with and without obesity class III receiving neuraxial morphine for post-cesarean analgesia: a retrospective cohort study – https://pubmed.ncbi.nlm.nih.gov/34053816/
Prospective Observational Investigation of Capnography and Pulse Oximetry Monitoring After Cesarean Delivery With Intrathecal Morphine – https://pubmed.ncbi.nlm.nih.gov/29958217/
Incidence of respiratory depression after epidural administration of morphine for cesarean delivery: findings using a continuous respiratory rate monitoring system https://pubmed.ncbi.nlm.nih.gov/30477999/
Enough But Not Too Much: Monitoring for Neuraxial Morphine-Associated Respiratory Depression in Obstetric Patients – https://pubmed.ncbi.nlm.nih.gov/31313670/
Society for Obstetric Anesthesia and Perinatology Consensus Statement: Monitoring Recommendations for Prevention and Detection of Respiratory Depression Associated With Administration of Neuraxial Morphine for Cesarean Delivery Analgesia – https://pubmed.ncbi.nlm.nih.gov/31082964/

Patient Reported Outcome Measurements (PROM)

Patient Reported Outcome Measurements (PROM)

In this episode, Dr. Pervez Sultan, a leading expert in creating obstetric Patient Reported Outcome Measurements (PROMs), including the validated Obstetric quality of recovery (OBsQoR-10), discusses their future in our field. And let me tell you, their future is PROMising, from using it as a benchmark score to compare amongst institutions to analyzing results between obstetricians and anesthesiologists alike to explore which technique(s) (e.g., uterus exteriorization vs. no exteriorization; intrathecal morphine doses) provide the best functional recovery for our patients.
Here are the links to the papers discussed during our Podcast:

Scoping review of postpartum recovery measures – https://pubmed.ncbi.nlm.nih.gov/32442292/
Proposed domains of postpartum recovery https://pubmed.ncbi.nlm.nih.gov/34536324/
Best measures of postpartum:
Global recovery – https://pubmed.ncbi.nlm.nih.gov/34042993/
Pain https://pubmed.ncbi.nlm.nih.gov/34016441/
Sleep – https://pubmed.ncbi.nlm.nih.gov/34013345/
Depression https://pubmed.ncbi.nlm.nih.gov/35749118/
Anxiety https://pubmed.ncbi.nlm.nih.gov/37402438/
ERAC – Beyond the pain scores https://pubmed.ncbi.nlm.nih.gov/32585468/
Obstetric Quality of Recovery-10 item measure
​UK multicenter cohort study https://pubmed.ncbi.nlm.nih.gov/37226593/
US https://pubmed.ncbi.nlm.nih.gov/33345919/
​Portuguese https://pubmed.ncbi.nlm.nih.gov/35487408/
​Turkish https://pubmed.ncbi.nlm.nih.gov/36301286/
Hebrew https://pubmed.ncbi.nlm.nih.gov/37717463/
Japanese https://pubmed.ncbi.nlm.nih.gov/37334251/
Core outcome set for ERAC https://pubmed.ncbi.nlm.nih.gov/35511169/