As you may have heard, mitochondria is the powerhouse of the cell! This is a phrase commonly mentioned in introductory biology textbooks and reiterated throughout our lives in an effort to prove that we do, in fact, remember something from high school biology. The first published manuscript to announce this was written by Dr. Philip Siekevitz and published in the Scientific American in 1957. It’s a short review with multiple images taken an electron microscope to confirm Dr. Siekevitz statement that the mitochondria’s form mirrors its function. However, research on mitochondria began almost exactly a century before this powerhouse statement was made…
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Sources:
Emma
-Investigation of fungi circadian rhythms in space: Sulzman FM, et al. Neurospora circadian rhythms in space: a reexamination of the endogenous-exogenous question. Science. 1984 Jul 13;225:232-4
-A 2008 interview with Michel Siffre: http://www.cabinetmagazine.org/issues/30/foer.php
Ellen
– Hadza chronotype study: Samson DR, et al. Chronotype variation drives night-time sentinel-like behaviour in hunter-gatherers. Proc Biol Sci. 2017;284(1858):20170967. doi:10.1098/rspb.2017.0967
– Chronotype GWAS: Jones, S. E., et al. (2019). “Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.” Nat Commun 10(1): 343.
Carrie
– General thoughts on why we sleep and the 4 hypotheses from: Siegel, Nature Reviews Neuroscience, 2009; Russel Foster, TED Global. 2013; Matthew Walker. Why We Sleep. 2017.
– Definition of sleep from: Rasch and Born, Physiol Rev. 2013
– Jellyfish study: Nath et al., 2017, Current Biology 27, 2984–2990
– Human asymmetrical sleep study: Tamaki et. al, Current Biology, 2016.
Elizabeth
– NPR “The Haunting Effects of Going Days Without Sleep”
– Coren S. “Sleep Deprivation, Psychosis, and Mental Efficiency.” (1998) Psychiatric Times, 15:3
– Everson CA, Bergmann BM, & Rechtschaffen A. “Sleep Deprivation in the Rat: II. Methodology.” (1989) Sleep. 12(1):5-12.
– Everson CA, Bergmann BM, & Rechtschaffen A. “Sleep Deprivation in the Rat: III. Total Sleep Deprivation.” (1989) Sleep. 12(1):13-21
– helathysleep.med.harvard.edu
– Fitzgerald, CT et al. “Teen sleep and suicidality: results from the youth risk behavior surveys of 2007 and 2009.” Journal of clinical sleep medicine: JCSM: official publication of the American Academy of Sleep Medicine vol. 7,4 (2011): 351-6. doi:10.5664/JCSM.1188
– Beccuti, G, & Pannain, S. (2011). Sleep and obesity. Current opinion in clinical nutrition and metabolic care, 14(4), 402–412. doi:10.1097/MCO.0b013e3283479109
– Bryant et al. (2004). “Sick and tired: Does sleep have a vital role in the immune system?” Nat Rev Immunol. 4(6):457-67. doi:10.1038/nri1369
– http://healthysleep.med.harvard.edu/healthy/matters/consequences/sleep-and-disease-risk
– Perils et al. (2016) “Suicide and sleep: Is it a bad thing to be awake when reason sleeps?” Sleep Med Rev. 29:101-7. doi:10.1016/j.smrv.2015.10.003
– Llorens, et al. (2017) “Fatal Familial Insomnia: Clinical Aspects and Molecular Alterations.” Curr Neurol Neurosci Rep. 17(4):30. doi:10.1007/s11910-017-0743-0
– The Better Sleep Council
YJBM editors Kartiga and Huaqi interview Dr. Robert Hahn, an epidemiologist at the Centers for Disease Control and Prevention (CDC), about self-motivated education. For more information about YJBM or to read our latest issues, visit medicine.yale.edu/yjbm
In the second episode for YJBM’s Clocks and Cycles Issue, Huaqi and Wei interview Xiaoyong Yang, an expert on the interactions between the circadian clock and metabolism. For more information about YJBM or to read the Clocks and Cycles issue, visit medicine.yale.edu/yjbm
To celebrate the Yale Journal of Biology & Medicine’s 90th anniversary, the outgoing editor-in-chief and managing editor discuss the value of YJBM and reflect on its history with YJBM’s faculty advisor, Professor Jeffrey Bender, and Yale School of Medicine’s Deputy Dean for Education, Dean Richard Belitsky. To find out more about YJBM, please visit our website at yjbm.yale.edu. To support other student-run, scientific journals, please also check out the Georgetown Medical Review at gmr.georgetown.edu.
Do you feel like you get sick more often when you aren’t getting enough sleep or when you travel overseas? There might be a reason for that! For the first episode based on YJBM’s Clocks and Cycles issue, join the Yale Journal of Biology and Medicine hosts, Amelia and Lisa, as they interview Dr. Silver about his work on how the circadian clock impacts your immune system. For more information about YJBM or to read the Clocks and Cycles issue, visit medicine.yale.edu/yjbm
The Yale Journal of Biology and Medicine Podcast hosts will interview Dr. Thomas Brown, a former Yale professor and current member of the clinical faculty of the Keck Medical School at the University of Southern California. Listen as we discuss Dr. Brown’s research and his work running an ADHD clinic.
Pay attention! Join Amelia Hallworth and Kelsie Cassell as they discuss attention science throughout life. We start with the neuroscience behind attention as a baby, discuss how children and adult’s attention is altered by technology, and finally look at the loss of attention in Alzheimer’s patients at the end of life. This episode is released in conjunction with and will feature research from the Yale Journal of Biology and Medicine’s March 2019 issue on Attention Science.
In the third installment of Yale Journal of Biology & Medicine’s series on ecology and evolution, YJBM podcast hosts Neal Ravindra and Kartiga Selvaganesan interview Richard Prum. Professor Prum is the William Robertson Coe Professor of Ornithology, a faculty member in Ecology and Evolutionary Biology, and affiliated with Yale’s Peabody Museum of Natural History. He is also the author of the recent book, The Evolution of Beauty, which was a finalist for the 2018 Pulitzer prize. We discuss some of the concepts in that book and topics in his current research program during the episode.
Yale Journal of Biology and Medicine podcast hosts, Amelia Hallworth and Kelsie Cassell provide a broad overview of the topics of ecology and evolution and highlight some of the research published in YJBM’s December 2018 issue focusing on Ecology and Evolution.